Biology

The correct answer is: D.On the plasma membrane.

Explanation:

1.Hydrophilic, protein-based hormones (such as peptide hormones) are water-soluble and cannot easily cross the lipid bilayer of the cell membrane. Therefore, their receptors are typically located on the plasma membrane of the target cell.

2.When the hormone binds to its receptor on the plasma membrane, it triggers a series of intracellular signaling even...